{"id":859,"date":"2026-08-21T13:07:51","date_gmt":"2026-08-21T05:07:51","guid":{"rendered":"https:\/\/eczema.skinmedical.com.hk\/evidence-based-treatment\/"},"modified":"2026-08-28T16:09:19","modified_gmt":"2026-08-28T08:09:19","slug":"evidence-based-treatment","status":"publish","type":"page","link":"https:\/\/eczema.skinmedical.com.hk\/en\/evidence-based-treatment\/","title":{"rendered":"Evidence-based treatment"},"content":{"rendered":"<div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-68f02a67\" data-vce-do-apply=\"all el-68f02a67\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-66-66p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-4b265329\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-4b265329\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-4b265329\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-2ed25aa6\" data-vce-do-apply=\"all el-2ed25aa6\"><h2><span style=\"color: #808080;\">\u6fd5 \u75b9&nbsp;<\/span><\/h2><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-9f508632\" data-vce-do-apply=\"all el-9f508632\"><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-63fe7ffd\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-63fe7ffd\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-63fe7ffd\"><div class=\"vce vce-separator-container vce-separator--align-center vce-separator--style-solid\" id=\"el-9b1e8bc5\" data-vce-do-apply=\"margin el-9b1e8bc5\"><div class=\"vce-separator vce-separator--color-bfc0c1 vce-separator--width-100 vce-separator--thickness-1\" data-vce-do-apply=\"border padding background  el-9b1e8bc5\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-8d1d5efc\" data-vce-do-apply=\"all el-8d1d5efc\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-22-12p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-9554b94c\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-9554b94c\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-9554b94c\"><div class=\"vce-single-image-container vce-single-image--align-center\"><div class=\"vce vce-single-image-wrapper\" id=\"el-038ed485\" data-vce-do-apply=\"all el-038ed485\"><figure><div class=\"vce-single-image-figure-inner\" style=\"width: 400px;\"><div class=\"vce-single-image-inner vce-single-image--absolute\" style=\"width: 100%; padding-bottom: 66.75%;\"><img loading=\"lazy\" decoding=\"async\" class=\"vce-single-image\"  width=\"400\" height=\"267\" srcset=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2024\/05\/photo-1586282091736-c2f9a8af8772-320x214.jpg 320w, https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/photo-1586282091736-c2f9a8af8772-400x267.jpg 400w\" src=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/photo-1586282091736-c2f9a8af8772-400x267.jpg\" data-img-src=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2024\/05\/photo-1586282091736-c2f9a8af8772.jpg\" data-attachment-id=\"312\"  alt=\"\" title=\"\" \/><\/div><\/div><figcaption hidden=\"\"><\/figcaption><\/figure><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-77-86p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-81ae1de0\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-81ae1de0\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-81ae1de0\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-e972d5ac\" data-vce-do-apply=\"all el-e972d5ac\"><h3><strong><span style=\"color: #756464;\"><span style=\"color: #756464;\">Atopic dermatitis (Eczema): Evidence-based treatment<\/span><\/span><\/strong><\/h3>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #756464;\"><span style=\"font-size: 15pt;\">The framework is a treatment ladder, and every level continues the one beneath it. Emollients never stop. Treatment ladder: <\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-10 vce-row-equal-height vce-row-content--top\" id=\"el-54a3569c\" data-vce-do-apply=\"all el-54a3569c\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-86686d1a\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-86686d1a\" vce-box-shadow=\"el-86686d1a\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-86686d1a\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-edd3c370\" data-vce-do-apply=\"all el-edd3c370\"><div style=\"text-align: center;\" align=\"center\">\n<table style=\"border-collapse: collapse; width: 93%; margin-right: calc(7%); border: medium none currentcolor;\">\n<tbody>\n<tr>\n<td style=\"color: #efefef; background-color: #efefef; border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><span style=\"color: #756464; font-size: 16px;\"><strong><span style=\"font-family: 'Google Sans', sans-serif;\">Step<\/span><\/strong><\/span><\/td>\n<td style=\"color: #efefef; background-color: #efefef; border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px;\"><strong><span style=\"font-family: 'Google Sans', sans-serif;\">Treatment<\/span><\/strong><\/span><\/td>\n<td style=\"color: #efefef; background-color: #efefef; border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px;\"><strong><span style=\"font-family: 'Google Sans', sans-serif;\">Indication<\/span><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/evidence-based-treatment\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Foundation<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Emollients, bathing practice, trigger avoidance<\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Everyone, always<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step1\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Step 1<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Topical corticosteroids; topical calcineurin inhibitors<\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Mild-to-moderate; flare treatment<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step2\/\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Step 2<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Proactive maintenance twice weekly; non-steroidal topicals (PDE4 inhibitors, topical JAK, tapinarof)<\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Recurrent flares at the same sites<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step3\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Step 3<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\"><strong>Narrowband UVB phototherapy<\/strong><\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Moderate disease inadequately controlled by topicals; useful steroid-sparing option<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step4\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Step 4<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Conventional systemics: ciclosporin, methotrexate, azathioprine, mycophenolate<\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Moderate-to-severe<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 17.3819%;\"><a href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step5\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #756464; font-size: 16px;\"><span style=\"font-family: 'Google Sans', sans-serif;\"><strong>Step 5<\/strong><\/span><\/span><\/a><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; width: 40.867%; text-align: center;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Biologics; oral JAK inhibitors<\/span><\/td>\n<td style=\"border: 0.75pt solid #c4c7c5; text-align: center; width: 41.7646%;\"><span style=\"color: #756464; font-size: 16px; font-family: 'Google Sans', sans-serif;\">Moderate-to-severe inadequately controlled by the above<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-10 vce-row-equal-height vce-row-content--top\" id=\"el-c83e0ed2\" data-vce-do-apply=\"all el-c83e0ed2\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-25p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-61f64bd5\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-61f64bd5\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-61f64bd5\"><div class=\"vce-single-image-container vce-single-image--align-left\"><div class=\"vce vce-single-image-wrapper\" id=\"el-c3b0a926\" data-vce-do-apply=\"all el-c3b0a926\"><figure><div class=\"vce-single-image-figure-inner\" style=\"width: 900px;\"><div class=\"vce-single-image-inner vce-single-image--absolute\" style=\"width: 100%; padding-bottom: 100%;\"><img loading=\"lazy\" decoding=\"async\" class=\"vce-single-image\"  width=\"900\" height=\"900\" srcset=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101-320x320.png 320w, https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101-480x480.png 480w, https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101-800x800.png 800w, https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101-900x900.png 900w\" src=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101-900x900.png\" data-img-src=\"https:\/\/eczema.skinmedical.com.hk\/wp-content\/uploads\/2026\/08\/eczema101.png\" data-attachment-id=\"659\"  alt=\"Eczema treatment \u6fd5\u75b9\u6cbb\u7642\u9999\u6e2f\" title=\"Eczema treatment\" \/><\/div><\/div><figcaption hidden=\"\"><\/figcaption><\/figure><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-75p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-6226340a\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-6226340a\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-6226340a\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-7bc048cf\" data-vce-do-apply=\"all el-7bc048cf\"><h2><span style=\"color: #756464;\">Foundation: emollients and skin care<\/span><\/h2>\n<p><span style=\"color: #756464;\">Unglamorous, and the single most important intervention. Emollients reduce flare frequency, reduce the amount of topical steroid needed, and improve comfort.<\/span><\/p>\n<\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-c537deb2\" data-vce-do-apply=\"all el-c537deb2\"><ul>\n \t<span style=\"color: #756464;\">\n<li><span style=\"color: #756464;\"><strong>Quantity is the issue, not brand.<\/strong> Adults need roughly 250\u2013500 g per week for widespread involvement; most people use a fraction of that. Under-application is the commonest reason emollients \"don't work.\"<\/span><\/li>\n<li><strong>Apply at least twice daily<\/strong>, and always within a few minutes of bathing.<\/li>\n<li><strong>Apply downwards<\/strong> in the direction of hair growth, to reduce folliculitis.<\/li>\n<li><strong>Match the vehicle to the season<\/strong>. Hong Kong's summer humidity makes heavy ointments intolerable \u2014 a lighter cream or lotion that is actually used beats a rich ointment that is abandoned in June. In winter, and in air-conditioned offices year-round, richer preparations work better.<\/li>\n<li><strong>Ointment for night, cream for day<\/strong> is a practical compromise many patients settle on.<\/li>\n<li><strong>Bathing<\/strong>: short, lukewarm \u2014 not hot. Hot showers feel wonderful on itchy skin and make it markedly worse. Use a soap substitute; avoid bubble bath and fragranced products.<\/li>\n<\/span><\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-10 vce-row-equal-height vce-row-content--top\" id=\"el-27b72982\" data-vce-do-apply=\"all el-27b72982\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-489aeac0\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-489aeac0\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-489aeac0\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-447d6078\" data-vce-do-apply=\"all el-447d6078\"><p><span style=\"color: #756464;\"><strong>On prevention<\/strong>: daily emollient from birth was widely hoped to prevent eczema in high-risk infants. The large randomised trials that tested this \u2014 including BEEP and PreventADALL \u2014 did not show a preventive benefit. Emollients remain essential for treating eczema; the evidence does not support them as a preventive measure in babies. I mention this because the opposite is still often stated.<\/span><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-10 vce-row-equal-height vce-row-content--top\" id=\"el-7ddf8c3a\" data-vce-do-apply=\"all el-7ddf8c3a\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-dcbb26ca\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-dcbb26ca\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-dcbb26ca\"><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-content--top\" id=\"el-85934969\" data-vce-do-apply=\"all el-85934969\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-20p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-f14b0517\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-f14b0517\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-f14b0517\"><div class=\"vce-features vce-var-icon vce-features--style-filled-circle vce-features--size-small\" style=\"--iconAlignment: center; --iconColor: rgb(255, 255, 255); --iconColorHover: #fff; --shapeColor: rgb(175, 163, 150); --shapeColorHover: rgb(218, 218, 218); --linkColorHover: rgb(157,146,134);\"><div id=\"el-c147ad58\" class=\"vce vce-features-icon-wrapper\" data-vce-do-apply=\"all el-c147ad58\"><a class=\"vce-features--icon vce-icon\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step1\/\" title=\"\u7b2c\u4e00\u7d1a: \u5916\u7528\u6297\u708e\u6cbb\u7642\" target=\"_blank\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 769 769\"><path stroke-width=\"25\" d=\"M565.755 696.27h-360l-180-311.77 180-311.77h360l180 311.77z\"><\/path><\/svg><span class=\"vce-icon-container vcv-ui-icon-dripicons vcv-ui-icon-dripicons-brush\"><\/span><\/a><\/div><\/div><div class=\"vce-google-fonts-heading vce-google-fonts-heading--align-center vce-google-fonts-heading--color-b-62-61-61--45--5C00FF--FF7200 vce-google-fonts-heading--font-family-Sanchez\"><div id=\"el-f7773c0d\" class=\"vce-google-fonts-heading-wrapper\"><div class=\"vce-google-fonts-heading--background vce\" data-vce-do-apply=\"border background  padding margin el-f7773c0d\"><h2 class=\"vce-google-fonts-heading-inner\" style=\"font-size: 20px; letter-spacing: 2px; font-weight: 400; font-style: normal;\">Step 1: Topical anti-inflammatory treatment<\/h2><\/div><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-1f397dae\" data-vce-do-apply=\"all el-1f397dae\"><p><span style=\"color: #756464; font-size: 14pt;\">Topical corticosteroids remain first-line for flares and have decades of evidence behind them. Learn more...<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-20p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first\" id=\"el-df254aaa\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-df254aaa\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-df254aaa\"><div class=\"vce-features vce-var-icon vce-features--style-filled-circle vce-features--size-small\" style=\"--iconAlignment: center; --iconColor: rgb(255, 255, 255); --iconColorHover: #fff; --shapeColor: rgb(175, 163, 150); --shapeColorHover: rgb(218, 218, 218); --linkColorHover: rgb(157,146,134);\"><div id=\"el-e10ca9df\" class=\"vce vce-features-icon-wrapper\" data-vce-do-apply=\"all el-e10ca9df\"><a class=\"vce-features--icon vce-icon\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step2\/\" title=\"\u7b2c\u4e8c\u7d1a: \u4e3b\u52d5\u7dad\u6301\u6cbb\u7642\" target=\"_blank\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 769 769\"><path stroke-width=\"25\" d=\"M565.755 696.27h-360l-180-311.77 180-311.77h360l180 311.77z\"><\/path><\/svg><span class=\"vce-icon-container vcv-ui-icon-batch vcv-ui-icon-batch-plus\"><\/span><\/a><\/div><\/div><div class=\"vce-google-fonts-heading vce-google-fonts-heading--align-center vce-google-fonts-heading--color-b-62-61-61--45--5C00FF--FF7200 vce-google-fonts-heading--font-family-Sanchez\"><div id=\"el-e50cc752\" class=\"vce-google-fonts-heading-wrapper\"><div class=\"vce-google-fonts-heading--background vce\" data-vce-do-apply=\"border background  padding margin el-e50cc752\"><h2 class=\"vce-google-fonts-heading-inner\" style=\"font-size: 20px; letter-spacing: 2px; font-weight: 400; font-style: normal;\">Step 2: Proactive maintenance<\/h2><\/div><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-6cf25bed\" data-vce-do-apply=\"all el-6cf25bed\"><p><span style=\"color: #756464; font-size: 14pt;\">The step most often skipped: This is the difference between eczema that recurs every few weeks and eczema that stays quiet. Learn more...<br>\n<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-20p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first\" id=\"el-5374d2df\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-5374d2df\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-5374d2df\"><div class=\"vce-features vce-var-icon vce-features--style-filled-circle vce-features--size-small\" style=\"--iconAlignment: center; --iconColor: rgb(255, 255, 255); --iconColorHover: #fff; --shapeColor: rgb(175, 163, 150); --shapeColorHover: rgb(237, 237, 237); --linkColorHover: rgb(157,146,134);\"><div id=\"el-30e1c272\" class=\"vce vce-features-icon-wrapper\" data-vce-do-apply=\"all el-30e1c272\"><a class=\"vce-features--icon vce-icon\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step3\/\" title=\"\u7b2c\u4e09\u7d1a: \u7a84\u983b NB-UVB \u5149\u7642\" target=\"_blank\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 769 769\"><path stroke-width=\"25\" d=\"M565.755 696.27h-360l-180-311.77 180-311.77h360l180 311.77z\"><\/path><\/svg><span class=\"vce-icon-container vcv-ui-icon-dripicons vcv-ui-icon-dripicons-vibrate\"><\/span><\/a><\/div><\/div><div class=\"vce-google-fonts-heading vce-google-fonts-heading--align-center vce-google-fonts-heading--color-b-62-61-61--45--5C00FF--FF7200 vce-google-fonts-heading--font-family-Sanchez\"><div id=\"el-d4939e03\" class=\"vce-google-fonts-heading-wrapper\"><div class=\"vce-google-fonts-heading--background vce\" data-vce-do-apply=\"border background  padding margin el-d4939e03\"><h2 class=\"vce-google-fonts-heading-inner\" style=\"font-size: 20px; letter-spacing: 2px; font-weight: 400; font-style: normal;\">Step 3: NB-UVB Phototherapy<\/h2><\/div><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-62cbcb0f\" data-vce-do-apply=\"all el-62cbcb0f\"><p><span style=\"color: #756464; font-size: 14pt;\">NB-UVB (311 nm) is a well-established treatment for moderate atopic dermatitis not adequately controlled by topical therapy, and it occupies a genuinely useful position on the ladder: more effective than topicals alone, without the systemic exposure of tablets or injections.Learn more...<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-20p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first\" id=\"el-129293c8\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-129293c8\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-129293c8\"><div class=\"vce-features vce-var-icon vce-features--style-filled-circle vce-features--size-small\" style=\"--iconAlignment: center; --iconColor: rgb(255, 255, 255); --iconColorHover: #fff; --shapeColor: rgb(175, 163, 150); --shapeColorHover: rgb(237, 237, 237); --linkColorHover: rgb(157,146,134);\"><div id=\"el-64285654\" class=\"vce vce-features-icon-wrapper\" data-vce-do-apply=\"all el-64285654\"><a class=\"vce-features--icon vce-icon\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step4\/\" title=\"\u7b2c\u56db\u7d1a: \u50b3\u7d71\u7cfb\u7d71\u6027\u6cbb\u7642\" target=\"_blank\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 769 769\"><path stroke-width=\"25\" d=\"M565.755 696.27h-360l-180-311.77 180-311.77h360l180 311.77z\"><\/path><\/svg><span class=\"vce-icon-container vcv-ui-icon-mfglabs vcv-ui-icon-mfglabs-link\"><\/span><\/a><\/div><\/div><div class=\"vce-google-fonts-heading vce-google-fonts-heading--align-center vce-google-fonts-heading--color-b-62-61-61--45--5C00FF--FF7200 vce-google-fonts-heading--font-family-Sanchez\"><div id=\"el-f696af9c\" class=\"vce-google-fonts-heading-wrapper\"><div class=\"vce-google-fonts-heading--background vce\" data-vce-do-apply=\"border background  padding margin el-f696af9c\"><h2 class=\"vce-google-fonts-heading-inner\" style=\"font-size: 20px; letter-spacing: 2px; font-weight: 400; font-style: normal;\">Step 4: Conventional systemic treatment<\/h2><\/div><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-a40cf2b2\" data-vce-do-apply=\"all el-a40cf2b2\"><p><span style=\"color: #756464; font-size: 14pt;\">For moderate-to-severe disease when the above is insufficient. All require baseline and ongoing blood monitoring.<\/span><\/p><p><span style=\"color: #756464; font-size: 14pt;\"><strong>Oral corticosteroids deserve a specific warning<\/strong>. They work rapidly and are therefore tempting, but eczema characteristically rebounds worse than before when they stop. Learn more.<\/span><\/p><\/div><\/div><\/div><\/div><\/div><div class=\"vce-col vce-col--md-20p vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last\" id=\"el-af14b39f\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-af14b39f\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-af14b39f\"><div class=\"vce-features vce-var-icon vce-features--style-filled-circle vce-features--size-small\" style=\"--iconAlignment: center; --iconColor: rgb(255, 255, 255); --iconColorHover: #fff; --shapeColor: rgb(175, 163, 150); --shapeColorHover: rgb(237, 237, 237); --linkColorHover: rgb(157,146,134);\"><div id=\"el-15664954\" class=\"vce vce-features-icon-wrapper\" data-vce-do-apply=\"all el-15664954\"><a class=\"vce-features--icon vce-icon\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/treatment-step5\/\" title=\"\u7b2c\u4e94\u7d1a: \u751f\u7269\u88fd\u5291\u8207\u53e3\u670d JAK \u6291\u5236\u5291\" target=\"_blank\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 769 769\"><path stroke-width=\"25\" d=\"M565.755 696.27h-360l-180-311.77 180-311.77h360l180 311.77z\"><\/path><\/svg><span class=\"vce-icon-container vcv-ui-icon-dripicons vcv-ui-icon-dripicons-pulse\"><\/span><\/a><\/div><\/div><div class=\"vce-google-fonts-heading vce-google-fonts-heading--align-center vce-google-fonts-heading--color-b-62-61-61--45--5C00FF--FF7200 vce-google-fonts-heading--font-family-Sanchez\"><div id=\"el-07b58b86\" class=\"vce-google-fonts-heading-wrapper\"><div class=\"vce-google-fonts-heading--background vce\" data-vce-do-apply=\"border background  padding margin el-07b58b86\"><h2 class=\"vce-google-fonts-heading-inner\" style=\"font-size: 20px; letter-spacing: 2px; font-weight: 400; font-style: normal;\">Step 5: Biologics and oral JAK inhibitors<\/h2><\/div><\/div><\/div><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-a356e786\" data-vce-do-apply=\"all el-a356e786\"><p><span style=\"color: #756464; font-size: 14pt;\">This is where atopic dermatitis treatment has changed beyond recognition. These advances represent the most significant treatment breakthroughs in dermatology in over a decade.<\/span><\/p>\n<p><span style=\"color: #756464; font-size: 14pt;\">Biologics are injected antibodies that block a single inflammatory signal. Learn more...<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"vce-row-container\" data-vce-boxed-width=\"true\"><div class=\"vce-row vce-row--col-gap-30 vce-row-equal-height vce-row-content--top\" id=\"el-3be7b09f\" data-vce-do-apply=\"all el-3be7b09f\"><div class=\"vce-content-background-container\"><\/div><div class=\"vce-row-content\" data-vce-element-content=\"true\"><div class=\"vce-col vce-col--md-auto vce-col--xs-1 vce-col--xs-last vce-col--xs-first vce-col--sm-last vce-col--sm-first vce-col--md-last vce-col--lg-last vce-col--xl-last vce-col--md-first vce-col--lg-first vce-col--xl-first\" id=\"el-5a00d247\"><div class=\"vce-col-inner\" data-vce-do-apply=\"border margin background  el-5a00d247\"><div class=\"vce-col-content\" data-vce-element-content=\"true\" data-vce-do-apply=\"padding el-5a00d247\"><div class=\"vce-text-block\"><div class=\"vce-text-block-wrapper vce\" id=\"el-1548ac6e\" data-vce-do-apply=\"all el-1548ac6e\"><p><span style=\"color: #756464; font-size: 12pt;\">Reference:<\/span><\/p>\n<ol>\n \t<span style=\"color: #756464; font-size: 12pt;\">\n<li><span style=\"color: #756464; font-size: 12pt;\">Davis DMR, Drucker AM, Alikhan A, et al. AAD guidelines of care for the management of atopic dermatitis in adults with topical therapies. J Am Acad Dermatol. 2023.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Sidbury R, Alikhan A, Bercovitch L, et al. AAD guidelines of care for the management of atopic dermatitis in adults with phototherapy and systemic therapies. J Am Acad Dermatol. 2023.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Guidelines Development Panel of the Hong Kong College of Paediatricians. Management of Atopic Dermatitis in Children: 2020 Review. HK J Paediatr. 2021;26:42-57. \u2014 the key local reference; cite this prominently.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Wollenberg A, Kinberger M, Arents B, et al. EuroGuiDerm guideline on atopic eczema. J Eur Acad Dermatol Venereol. (most recent update).<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">National Institute for Health and Care Excellence. Atopic eczema in under 12s: diagnosis and management. CG57.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Leung R, Wong G, Lau J, et al. Prevalence of asthma and allergy in Hong Kong schoolchildren: an ISAAC study. Eur Respir J 1997.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Childhood Wheeze, Allergic Rhinitis, and Eczema in Hong Kong: ISAAC Study from 1995 to 2015. \u2014 source of the 21-year local trend data.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993;186:23-31.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial (ADhere). JAMA Dermatol.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">ARCADIA 1 and ARCADIA 2 \u2014 two identically designed pivotal phase III trials enrolling more than 1,700 patients, evaluating nemolizumab administered subcutaneously every four weeks versus placebo with background topical corticosteroids.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Sanofi. Press release: decision not to submit amlitelimab in atopic dermatitis for global regulatory reviews. Paris, 24 July 2026.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Simpson EL, Bieber T, Guttman-Yassky E, et al. Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis (SOLO 1 and SOLO 2). N Engl J Med. 2016.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Chalmers JR, et al. BEEP trial: daily emollient during the first year of life for preventing atopic dermatitis. Lancet. 2020. \u2014 the negative prevention trial cited in the article.<\/span><\/li>\n<li><span style=\"color: #756464; font-size: 12pt;\">Hong Kong Drug Office, Department of Health \u2014 verify local registration status of every systemic agent named.<\/span><\/li>\n<\/span><\/ol>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6fd5 \u75b9&nbsp;Atopic dermatitis (Eczema): Evidence-based treatment &nbsp; The framework is a treatment ladder, and every level continues the one beneath it. Emollients never stop. Treatment ladder: Step Treatment Indication Foundation Emollients, bathing practice, trigger avoidance Everyone, always Step 1 Topical corticosteroids; topical calcineurin inhibitors Mild-to-moderate; flare treatment Step 2 Proactive maintenance twice weekly; non-steroidal topicals&hellip; <a class=\"more-link\" href=\"https:\/\/eczema.skinmedical.com.hk\/en\/evidence-based-treatment\/\">Continue reading <span class=\"screen-reader-text\">Evidence-based treatment<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-859","page","type-page","status-publish","hentry","entry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Evidence-based treatment for Eczema<\/title>\n<meta name=\"description\" content=\"The framework is a treatment ladder, and every level continues the one beneath it. 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